Premier League 2025/26: Gameweek 10 Preview and Predictions

Gameweek 10 of the 2025/26 Premier League season arrives after another round of midweek EFL Cup action. There were mighty upsets in the last Gameweek as Chelsea, Manchester City, and Liverpool all lost — showcasing the kind of unpredictability that sets this league apart.

Some mouth-watering encounters await us this weekend, with Spurs hosting Chelsea, Liverpool welcoming the Villans, and the Cityzens hosting the Cherries. 

Here, we present our preview and predictions for Gameweek 10 of the 2025/26 Premier League season.

Crystal Palace vs Brentford 

Both the Eagles and the Bees won their midweek fixtures away in the League Cup. While Crystal Palace defeated a much-changed Liverpool side 3–0, Brentford humiliated Grimsby Town 5–0. Ismaïla Sarr scored a brace for Palace, while Brentford had five different scorers.

On the injury front, Palace have Caleb Kporha, Chadi Riad, Cheick Doucouré, and Chris Richards out, while Brentford are without Aaron Hickey, Gustavo Nunes, and Yehor Yarmoliuk due to injuries.

The League Cup win was Palace’s first win in five games, while Brentford have gained momentum recently with four wins out of five, which makes us confident that they’ll get at least a point here. Their defensive vulnerability can hurt them, though, and Palace are sufficiently potent up front to not leave Selhurst Park empty-handed.

Score prediction: Crystal Palace 1–1 Brentford 

Nottingham Forest vs Manchester United

While Forest must have been relieved with their recent Europa League victory over a high-flying Porto side, they lost to Bournemouth in the league last weekend, marking just one win in their last five games. Manchester United, on the other hand, have built some momentum, winning three in a row after a long time. Both teams did not play in midweek and will be well rested for this encounter.

In terms of player availability, Forest will be without Ola Aina, Chris Wood, Dilane Bakwa, and Oleksandr Zinchenko, while United will be without Harry Maguire and Lisandro Martínez.

Based on their recent struggles, Forest look nowhere close to the Europe-qualifying side from last season. Sean Dyche is already their third full-time boss this season after Ange Postecoglou was dismissed 39 days after taking over from Nuno Espírito Santo; it’s unlikely things change right away. United look more likely to come away with the three points here, with their new signings Bryan Mbeumo and Matheus Cunha looking like they’re finally starting to click.

Score prediction: Nottingham Forest 0–2 Man United 

Burnley vs Arsenal 

Burnley did not play in midweek, having already been knocked out of the Carabao Cup. Meanwhile, a heavily rotated Arsenal side secured a comfortable 2–0 victory against Brighton to reach the Carabao Cup quarter-finals.

As for players missing due to injuries, Burnley are without Connor Roberts, Zeki Amdouni, and Jordan Beyer, while the Gunners have long-term absentees in Gabriel Jesus and Kai Havertz, with Gabriel Martinelli, William Saliba, Noni Madueke, and Martin Ødegaard also doubtful for this game.

While the Clarets have won their last two league fixtures, those victories came against struggling sides — Leeds United and Wolves. Arsenal, on the other hand, look unbeatable and have won all of their last six encounters without conceding a goal. Even though Burnley will try to play a low block and make life difficult for them, Arsenal should be able to break their resistance while keeping another clean sheet.

Score prediction: Burnley 0–2 Arsenal

Brighton & Hove Albion vs Leeds United

Having lost to Arsenal in the League Cup, as well as having been beaten by Man United in the league last weekend, Brighton will look to get back to winning ways at home. Leeds’ last game, meanwhile, resulted in a 2–1 win against West Ham, though aside from that Leeds aren’t in great form either, having lost two league games before the win against the Hammers.

On the injury front, Brighton are in huge trouble, with Adam Webster, Brajan Gruda, Jack Hinshelwood, James Milner, Kaoru Mitoma, and Solly March all on the sidelines. Leeds, on the other hand, are faring much better, with only Gabriel Gudmundsson and Wilfried Gnonto unavailable against the Seagulls.

Injuries to first-choice players have undoubtedly played a part in Brighton’s recent poor form, but they do have defensive issues as well due to their playing style, which should give Leeds an opening or two, though it’s hard to see Brighton losing this game given their attacking strength.

Score prediction: Brighton 2–1 Leeds United 

Fulham vs Wolverhampton Wanderers          

While Wolves are bottom of the league table with three defeats and two draws in their last five games, Fulham have won just once in their last five league fixtures. They also just about got away in their midweek fixture against Wycombe Wanderers, winning on penalties to reach the League Cup quarter-finals. Wolves, meanwhile, put up a decent performance against a heavily rotated Chelsea side in midweek but lost the Carabao Cup encounter 3–4 at home.

Fulham have massive injury issues, with Antonee Robinson, Harry Wilson, Rodrigo Muniz, Joachim Andersen, and Samuel Chukwueze all out, while Wolves have all of their first-choice players available for this game.

With so many players out, Marco Silva will have to play a weakened side against Wolves, though playing at home means they have a great opportunity this weekend to get their form back. Ultimately, despite their absentees, this should be a comfortable win for the Cottagers, though Wolves may be able to grab a consolation goal.

Score prediction: Fulham 3–1 Wolves 

Tottenham Hotspur vs Chelsea  

In what is arguably the game of the weekend, London rivals Spurs and Chelsea will face off at Tottenham Hotspur Stadium this Saturday.

While Spurs lost to Newcastle United in their midweek EFL Cup fixture, Chelsea won a close encounter against Wolves. Spurs now have two defeats in their last five games, while the Blues have four wins and one defeat, which came at home to Sunderland last weekend.

In terms of player availability, Spurs have been very unlucky, with a host of players missing due to injury. While James Maddison and Radu Dragusin are out with long-term ACL injuries, Archie Gray, Yves Bissouma, Ben Davies, Cristian Romero, Dejan Kulusevski, Destiny Udogie, and Dominic Solanke are all unavailable for this game. Chelsea, meanwhile, have one long-term absentee in Levi Colwill, with Benoît Badiashile, Cole Palmer, and Dário Essugo also out for a while.

Given their huge list of absentees, Spurs are light in defence, which Chelsea could exploit. However, the Blues aren’t sound defensively either, which will encourage the likes of Mohammed Kudus, Xavi Simons, and Brennan Johnson in the Spurs camp. In the end, Chelsea should be able to edge this derby affair, though Spurs will not make it easy for them.

Score prediction: Spurs 1–2 Chelsea 

Liverpool vs Aston Villa

Arne Slot played a heavily rotated side against Crystal Palace in the EFL Cup and was handed another defeat, as the Eagles ran out 3–0 victors, while Villa didn’t play in midweek.

Injury-wise, Liverpool have a fair few players out, most notably Ryan Gravenberch, Curtis Jones, Alisson Becker, Jeremie Frimpong, and Alexander Isak, while the Villans have former Red Harvey Elliott suspended and Youri Tielemans and Emi Buendía out with injuries.

Looking at their recent form, Liverpool have suffered four straight defeats in the league, while Villa have gained momentum and won four league games in a row. Even though most of Liverpool’s first-choice players were rested in midweek, and given that this is a home fixture, recent results don’t suggest that they can turn around their dismal form with a win here. They may at least be able to stop their run of losses and grab a point, especially given Villa haven’t won at Anfield since 2014.

Score prediction: Liverpool 2–2 Aston Villa 

West Ham United vs Newcastle United

West Ham United’s change of personnel in management hasn’t yet resulted in a change in their fortunes. They still can’t win games, and have four losses and a draw from their last five outings. Newcastle United, on the other hand, have started to settle down and lost just one game in their last five fixtures across all competitions, having defeated Spurs in the EFL Cup as well this midweek.

In terms of player availability, West Ham have Konstantinos Mavropanos and Niclas Füllkrug unavailable, while the Magpies will be without Lewis Hall, Tino Livramento, and Yoane Wissa for this game.

Based on the fact that West Ham have shown minimal improvement in their performances despite a new head coach coming in, Newcastle are our overwhelming favourites for this game.

Score prediction: West Ham 0–2 Newcastle

Manchester City vs Bournemouth

While Man City won their Carabao Cup fixture against Swansea City in midweek, Bournemouth had a full rest ahead of this difficult fixture. City returned to winning ways after their defeat against Villa in the league last weekend, while Bournemouth secured a comfortable victory against Nottingham Forest last time out.

City have a few players coming back in the form of Omar Marmoush and Rayan Cherki, who will both bolster their attack, though they will be hoping that star striker Erling Haaland is fit for this game, with Rodri still out injured. Bournemouth, meanwhile, will be without Evanilson for this game.

The Cityzens have lost only one game in their last five fixtures, having won the other four, while the Cherries have three draws and two wins and are somewhat susceptible in defence. With Marmoush and Cherki back, City have a formidable attacking line that should be able to overpower the Bournemouth defence and secure all three points for the hosts.

Score prediction: Man City 2–1 Bournemouth 

Sunderland vs Everton

Both Sunderland and Everton were knocked out of the EFL Cup in the previous round and have a fully rested squad for this game. As for their results last weekend, the Black Cats stunned Chelsea at the Bridge with a late winner, while the Toffees were thrashed 3–0 at home by Spurs.

In terms of player availability, Sunderland still have many players out, with Romaine Mundle, Leo Hjelde, Dennis Cirkin, Ajibola Alese, Omar Alderete, and Habib Diarra all out with injuries. Everton, in comparison, only have Jarrad Branthwaite and Nathan Patterson missing for this encounter.

Sunderland are proving to be a tough side to play at home, and Everton’s poor away form further worsens their odds of getting anything from this game. David Moyes’ men do have the attacking prowess to hurt Sunderland, and yet, despite the potential of a close and feisty battle, all signs point to a Sunderland win.

Score prediction: Sunderland 2–1 Everton